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An incision was made under 2% isoflurane anesthesia delivered via a nose cone, as described by Brennan et al

Its deficiency causes oxidative stress that not only promotes the oxidation of proteins and deoxyribonucleic acid (DNA) but also leads to insulin resistance, dyslipidemia, inflammation, and metabolic alterations, which expose to high risk for cardiometabolic disorders due to cardiovascular and degenerative diseases especially when associated with aging

When taken by mouth, it is possibly safe when used in doses of up to 500 mg daily for up to two months

This study included patients who underwent radical PG-DTR or TG for pathological stage I gastric cancer