chac1 glutathione Dysregulated lipids homeostasis disrupts CHAC1-mediated ferroptosis driving fibroblast growth factor receptor tyrosine kinase inhibitor AZD4547 resistance in gastric cancer Glutathione-specific gamma–glutamylcyclotransferase 1 (CHAC1) increases

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und Halbach OV, Schober A, Krieglstein K (2004) Genes, proteins, and neurotoxins involved in Parkinsons disease

Disclosures: Ryo Sasaki: Nothing to Disclose, Tsuyoshi Ishikawa: Nothing to Disclose, Taro Takami: Nothing to Disclose 523 METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE IS ASSOCIATED WITH LIVER FIBROSIS IN HEPATITIS C Wesal Elgretli 1 Mohamed Shengir 1 Solomon Sasson 2 Ramanakumar Agnihotram V 3 Luz Esther Ramos Ballesteros 4 Marc Deschenes 5 Philip Wong 5 Tianyan Chen 5 Nadine Kronfli 6 Alexa Keeshan 7 Saniya Tandon 8 Curtis Cooper 8 Giada Sebastiani 9 , 1 Division of Experimental Medicine, McGill University, Montreal, Canada, 2 Department of Medicine, University of British Columbia, Vancouver, Canada, 3 Research Institute, McGill University Health Center, Montreal, Canada, 4 Chronic Viral Illness Services, McGill University Health Center, Montreal, Canada, 5 Department of Medicine, McGill University Health Centre, Montreal, Canada, 6 Chronic Viral Illness Service, McGill University Health Centre, Montreal, Canada, 7 Division of Infectious Diseases, Ottawa Hospital Research Institute, Ottawa, Canada, 8 Division of Infectious Diseases, Hospital Research Institute, Ottawa, Canada, 9 Chronic Viral Illness Service

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