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They have been extensively studied in large-scale human clinical trials, with robust safety data spanning over a decade

In this single study, researchers hypothesized that elevated serum selenium levels and reduced copper levels in patients with HTs and overt hypothyroidism might result in lower L-thyroxine dosages or reaching a euthyroid state with decreased free T4 due to the direct impact of the copper-selenium ratio on redox balance and as a result of thyroid health [109]

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I using one hand to pinch (or grab, perhaps!) the muscle and skin of my thigh, pulling it slightly away from the bone