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Local trends toward more record heat than cold are an indicator of climate change, and heat extremes put people and ecosystems at risk

Polyphenols frequently exhibit limited absorption rates and undergo rapid metabolism within the human body, hence constraining their capacity to reach and exert their effects on specific regions within the brain ( in vitro and animal models to clinical practice has been difficult due to the lack of replication of identified effects in human studies

Host defense peptides identified in human apolipoprotein B as promising antifungal agents

3.3 Evaluation of cytokines and chemokines in tears during clinical study As detailed in the materials and methods section of the manuscript, the concentration of different cytokines and chemokines in tears was analyzed using flow cytometry at four study visits following randomization: V1, V3 (1 month after the initial control or the experimental formulation treatment), V4 (after the 1-week wash-out), and V6 (1 month after the crossover treatment)