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first identified CCP1 as an essential regulator for neuronal survival, showing that Purkinje cell degeneration (PCD) mice lacking CCP1 accumulate hyperglutamylated MTs and rapidly lose Purkinje cells, followed by degeneration of olfactory and thalamic neurons [23]

102 A review of the clinical evidence found melatonin therapy can improve sleep in individuals with tinnitus, but was unable to determine conclusively whether it can improve tinnitus

Common signs of possible vitamin B12 deficiency can include fatigue or weakness, brain fog or memory issues, shortness of breath, pale or jaundiced skin, and tingling or numbness in the hands and feet

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