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Liu S, Li E, Sun Z, Fu D, Duan G, Jiang M, et al

Additionally, the inhibition of LRRK2 has been linked to reduced ferroptotic damage via the p62/Keap1/NRF2 axis (132) and teneligliptin, a dipeptidyl peptidase-4 inhibitor, decreases ROS levels and prevents ferroptosis (133)

Involvement of nerve growth factor (NGF) in chronic neuropathic pain a systematic review

ROS, such as superoxide (O 2 - ), can be produced in mitochondrial complexes I and III in components of the tricarboxylic-acid cycle, including -ketoglutarate dehydrogenase (EC 1.2.4.2), and in the outter mitochondrial membrane, damaging cell components such as lipids, proteins and DNA [25, 47]