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Supporting a dominant role for diet composition in establishing the Firmicutes : Bacteroidetes ratio, previous work has shown that mice maintained on a high-fat diet had a similar cecal Firmicutes : Bacteroidetes ratio to those maintained on a high-carbohydrate diet 77

Schep LJ, Slaughter RJ, Watts M, Mackenzie E, Gee P

People with certain medical conditions, such as kidney disease or Lebers hereditary optic neuropathy, should discuss methylcobalamin use with a healthcare professional before starting supplements

These trials tracked numerous safety parameters and laboratory values, but vitamin b12 levels were not routinely monitored or reported in the published results