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Histopathologically, psoriasis is characterized by infiltration of immune cells, epidermal hyperproliferation, and abnormal keratinocyte (KC) differentiation (9)

Another study reported that the inhibitory activity of NF-B is due to the binding of GS to the RH domain of NF-B precursor protein p105 containing important sequences for DNA binding and dimerization (Khan et al., 2013)