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Long-term oral studies of acetylcysteine alone in rats (12 months of treatment followed by 6 months of observation) at doses up to 1,000 mg/kg/day (5.2 times the human mucolytic dose) provided no evidence of oncogenic activity

Parkinsons disease Parkinsons disease named after James Parkinson who provided the first description of this disorder, 636 is characterised by progressive degeneration of dopaminergic midbrain neurones of the brainstem

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