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120 Mechanistically, EGCG treatment enhances STAT5 activation but attenuates STAT3 activation to promote regulatory T cell responses, thus mitigating Th17 responses in these obese models

Karathanasis, Targeted nanotechnology for cancer imaging

The integrated analysis of the experimental X-ray crystallography data herein presented with computational analysis and literature data on homologous enzymes strongly supports the identification of at least two druggable sites on SmTGR, i.e., sites S3 (doorstop) and S8, the later described for the first time here