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Systemic inflammation changes the site of RAGE expression from endothelial cells to neurons in different brain areas

This seems obvious when stated plainly, but under the cognitive load of a new protocol, people make this mistake more often than anyone wants to admit

Because the BDNF gene plays a central role in regulating neuronal survival, synaptic plasticity, and the formation of new neural connections, individuals with this genotype typically maintain normal neurotrophic signaling capacity within brain networks responsible for learning, memory, and emotional regulation

10.3390/toxins12070451 78 EltaherS.MohammedG