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Initial search criteria included alphalipoic acid + neuropathy and acetyl-L-carnitine + neuropathy. Preference for full-text review of search results was given to systematic reviews and randomized controlled trials, although other clinical trials and case reports were included, particularly if they contained relevant information for adverse reactions or contraindications to the use of either supplement

Preparation of samples For water-soluble materials, each sample was prepared by simply dissolving in distilled water

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CAT : carnitina-acil-transferasi , presente sulla membrana mitocondriale interna, trasferisce gruppi acile dall'acil-CoA alla carnitina, formando acil-carnitina, esportata dal CT