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However, due to the limited sample size and lack of long-term follow-up in existing studies, we lack an in-depth understanding of the impact and incidence of this complication

However, phosphorylated AKT (p-AKT) and phosphorylated p38 (p-p38), the activated forms of AKT and p38, remarkably decreased in HCT116 GSTA4 cells compared with HCT116 cells, indicating inhibition of AKT and p38 signaling pathways