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J., Kim, Y

Mucus dysfunction in the airways is common in primary chronic respiratory conditions such as asthma [7], chronic obstructive pulmonary disease (COPD) [8], cystic fibrosis (CF) [9], and lung cancer [10]

For example, lysosomes are programmed to monitor the intracellular levels of nutrients and energy, thus engaging in nutrient sensing, metabolic regulation, and cellular homeostatic maintenance by providing an initial platform for the activation of mammalian target of rapamycin complex 1 (mTORC1) and adenosine 5-monophosphate (AMP)-activated protein kinase (AMPK) 4

Additionally, you can be a cigarette smoker, be diabatic with an elevated A1C, have a heart condition you name it