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Therapeutic inhibition of the JAK-STAT pathway in the treatment of inflammatory bowel disease

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Notably, it has been found that silencing long noncoding RNAs (lncRNAs) nuclear paraspeckle assembly transcript 1 (NEAT1) promotes microRNA-129 and microRNA-204 inhibition of the MAPK/ERK signaling pathway and attenuates FLS synovitis in RA ( In addition to this, it is also important to alleviate the development of RA by down-regulating various cytokines

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Genes whose absolute value of the log2 (treated/control) ratio was greater than or equal to 1.2 and whose q -value was less than 0.001 were considered differentially expressed genes (DEGs)

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