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High serum manganese concentrations in female workers yielded a variety of effects, including increased activity of DNA oxidation products, increased incidence and variability of chromosome polymorphisms characterized by somatic genetic instability, and sex hormone imbalance (128)

This inhibition prevents the release and nuclear translocation of the NF-B p65 subunit, thereby attenuating downstream inflammatory signaling (256, 257)

[DOI] [PubMed] [Google Scholar] 55.Pazyar N., Houshmand G., Yaghoobi R., Hemmati A.A., Zeineli Z., Ghorbanzadeh B

A time-dependent increase could be observed which was more pronounced in the targeted nanocarriers groups