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However, Suzuki et al 174 found that strong ALDH1A1 expression was associated with better tumor differentiation and had little correlation with stem cell characteristics in HCC cells

In another experiment, alpha-tocopherol (T) and gamma-tocotrienol (T) were supplemented continuously for 8 weeks in the diets of normal rats and rats chemically induced with cancer using diethylnitrosamine (DEN), 2-acetylaminofluorene (AAF) and partial hepatectomy

The cells were then treated with the corresponding drugs added to each well as needed for the experiment, and the cells were cultured for an additional 24 h

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