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Metabolism 38 , 753758 (1989)

Specifically, in 3D bronchial tissues exposed to cigarette smoke, levels of key PPP intermediates (e.g., 6-phosphogluconate, erythrose-4-phosphate) are significantly elevated, while the activity of G6PD, which is the rate-limiting enzyme of the PPP, is enhanced

T h 17 and T h 22 cells, meanwhile, have been observed to display atheroprotective and proatherogenic effects and therefore warrant continued investigation