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Nature 572 , 538542 (2019)

The effect of probiotic supplementation on depressive symptoms and quality of life in patients after myocardial infarction: Results of a preliminary double-blind clinical trial

Piatkowska-Jakubas B, Krawczyk-Kuli M, Giebel S, et al

The brain, being highly dependent on glucose and oxygen delivered via cerebral blood flow, becomes especially vulnerable when cerebral blood flow declines due to aging or sleep deprivation, resulting in metabolic instability and overproduction of ROS (Leithner and Royl, 2014