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J Crohns Colitis 14(1):422 Chaparro M, Ords I, Cabr E, Garcia-Sanchez V, Bastida G, Pealva M et al (2013) Safety of thiopurine therapy in inflammatory bowel disease: long-term follow-up study of 3931 patients

However, like many other biological processes, aging is regulated by canonical signaling pathways and transcription factors, making it amenable to modulation through targeted interventions (Kenyon, 2010)