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Conversely, when GPX8 is silenced, the histamine-induced release of Ca 2+ from the endoplasmic reticulum to mitochondria and cytoplasm is increased (Yoboue et al., 2017)

Maternal hypothyroidism caused by iodine deficiency is associated with adverse pregnancy outcomes and impaired fetal growth, such as spontaneous abortion, premature birth, fetal death, low birth weight, neonatal mortality, growth restriction, altered cognitive development (cretinism, language disorders, altered motor development) [119]

These range from energy production and muscle movement to optimal brain function and improved mood

Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice