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It promotes youthful energy production in cells and crosses the blood-brain barrier to support brain and nervous system

Int Immunopharmacol 108:108852 Song Q, Jian W, Zhang Y et al (2024) Puerarin attenuates iron overload-induced ferroptosis in retina through a Nrf2-mediated mechanism

Key Points Chronic inflammation is prevalent in the adult prostate and probably has a role in the formation of lesions that are putative risk factors for prostate cancer development Prostatic inflammation might drive prostate carcinogenesis via oxidative stress and the generation of reactive oxygen species that induce mutagenesis or by causing epigenetic alterations that promote neoplastic transformation Prostatic infection might drive an inflammatory prostate microenvironment, and the discovery of a urinary microbiome is probably important in terms of exposure of the prostate to potentially pathogenic microorganisms Epithelial barrier disruption and inflammation in the prostate, once started, could establish a feed-forward mechanism resulting in a chronic, persistent inflammatory state Full characterization of the link between the urinary microbiome and chronic prostatic inflammation might be critical to enable the development of strategies for prostate cancer prevention Abstract Chronic inflammation promotes the development of several types of solid cancers and might contribute to prostate carcinogenesis

The association between carnitine levels and disorders such as depression, schizophrenia, and Alzheimers disease suggests that carnitine could be a valuable biomarker and therapeutic target