Serious Warning Signs Severe abdominal pain: Especially if sudden onset, radiating to back, or with vomiting (possible pancreatitis, occurred in 0.3% of patients) Severe vomiting: If unable to keep any fluids down for 24 hours (dehydration risk) Signs of dehydration: Dark urine, dizziness on standing, confusion, decreased urination (acute kidney injury risk) Vision changes: Blurred vision, eye pain (rare but requires evaluation) Rapid heart rate: Persistent heart rate over 100 at rest (some increase normal, average 2-4 bpm, but sustained tachycardia needs evaluation) Suicidal thoughts: Any thoughts of self-harm (under 1% occurrence but requires immediate support) Severe allergic reaction: Difficulty breathing, throat swelling, severe rash (anaphylaxis requires emergency care) Lump in neck: Especially with difficulty swallowing (thyroid concern, rare but part of class warning) Trust your instincts
10.1101/gr.7.2.108 6 AliR.Le MaitreC.RichardsonS.HoylandJ.FreemontA
Open Access REVIEW Curcumin in inflammatory bowel diseases: Cellular targets and molecular mechanisms 1 Rede Nordeste de Biotecnologia (RENORBIO), Instituto de qumica e Biotecnologia, Universidade Federal de Alagoas (UFAL), Macei, 57072-900, Brasil 2 Programa de Ps-graduao em Nutrio (PPGNUT), Faculdade de Nutrio (FANUT), Universidade Federal de Alagoas (UFAL), Macei, 57072-900, Brasil 3 Programa de Ps-Graduao em Qumica e Biotecnologia (PPGQB), Instituto de qumica e Biotecnologia, Universidade Federal de Alagoas (UFAL), Macei, 57072-900, Brasil 4 Colegiado de Nutrio, Universidade de Pernambuco (UPE), Campus Petrolina, Pernambuco, 56328-900, Brasil 5 Programa de Ps-Graduao em Cincias da Sade (PPGCS), Instituto de Cincias da Sade, Universidade Federal de Alagoas (UFAL), Macei, 57072-900, Brasil 6 Programa de Ps-graduao em Cincias Mdicas (PPGCM), Faculdade de Medicina, Universidade Federal de Alagoas (UFAL), Macei, 57072-900, Brasil * Corresponding Author: FABIANA ANDRA MOURA
Novel phenotypical and functional sub-classification of liver macrophages highlights changes in population dynamics in experimental mouse models
