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These higher buprenorphine C max were associated with an earlier median T max of 4.0 h and 7.0 h for the thigh and upper arm respectively, compared with 10 h and 16 h for the buttocks and abdomen (Supplementary Table 1)

While such evaluation is well beyond the scope of this study, we posit that collagen fibers in the epineurium and perineurium as well as individual nerve fibers, including axons and their surrounding basal lamina and endoneurial connective tissue, are the most likely scattering elements, based on prior data from our group detailing a strong correlation between iBSC and collagen and myelin levels in cadaveric nerves 31

It is the first and only bispecific antibody approved for the eye, according to Genentechs announcement

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