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Although this was the first description of the disease as a neurological condition, it was not until 50 years later that new scientific evidence obtained by Jean-Martin Charcot contributed to a definition of the clinical and anatomopathological basis of Parkinsons Disease (PD) (Charcot, 1872)

Unlike pharmacological- and immunological-based approaches, bacteriotherapy may provide an effective strategy that both treats, and prevents NTHi infections, which is not compromised by antigenic heterogeneity or bacterial resistance mechanisms