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Additionally, it has been discovered that TAZ serves as a genetic determinant of ferroptosis through the regulation of ANGPTL4-NOX2, thereby highlighting its potential as a novel therapeutic target for ovarian cancer and other TAZ-activated tumors (Yang et al., 2020)

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However, it also showed anti-inflammatory actions, such as inhibition of 5- and 15-lipoxygenases (LOX), NOS, and phagocyte-related ROS production (Day, 2008) (see Section 11.2)