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As a consequence of these observations, our results suggest that autophagy may be an adaptive response to continuous metabolic alterations and that its induction may result in a protective attempt to antagonize degenerative processes and to enhance survival in normal appearing vitiligo skin, where melanocytes and fibroblasts are already prone to premature senescence

For Arbutin_c, it stably interacts with four key residues: D180, E184, S165, and S361 (Table 2)

Diverticular disease, as a benign indication for colorectal surgery, may have a positive impact on patients with cirrhosis in certain situations

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