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Conversely, Vasconcelos et al

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This dual regulation of SLC7A11 expression and activity creates a fine-tuning mechanism to modulate cell antioxidant capacity and lipid ROS during ferroptosis ( (with erastin, sulfasalazine, or sorafenib) or GPX4 (with RSL3, ML162, ML210, FIN56, or FINO2) can produce ROS in the absence of GSH depletion and trigger ferroptosis

Regulatory neuropeptides in central nervous system function