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In models of peripheral nerve injury, NRN1 has been shown to undergo a redistribution from predominantly somatic localization to axonal compartments, suggesting a role in axonal regeneration and repair following neural damage (Merianda et al., 2013)

the contents are 3x as much as in a normal shot which is just likely to be excessive and result in more being flushed down the lavatory as the rate of loss is higher if you have more in your blood so more isn't necessarily better - and they are also suggesting a really high frequency of use which is also likely to be unnecessary

Zhang J, Guo L, Zhang Q, Liu K, Dong Z

doi: 10.1096/fj.04-3213fje