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Among these preliminary studies, one found that, in cultured cells, Protandim activated Nrf2, a protein that stimulates genes that respond to free radicals and oxidative stress, and another found it to improve markers of oxidative stress in mice (Reuland, Free Radic Biol Med 2013

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Critically ill patients are highly susceptible to dysbiosis of the gut microbiota due to factors such as antibiotic use, physiological stress, altered nutrition, and prolonged hospitalization ( Enterobacteriaceae and Enterococcaceae ( Victoria et al., 2022