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Results Confocal imaging reveals morphological alterations in AC16 cells following DOX exposure To study mitochondria-related cardiac toxicity, we first performed functional and morphological analyses of confocal images of the cardiac AC16 cell line treated with various types of mitochondrial inhibitors, including DOX (Fig

However, the extracellular concentration of this oxidant is difficult to predict, as it does not only depend on the amount of neutrophils in the inflammatory region, but also on the levels of MPO released during neutrophil activation and availability of H 2 O 2

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