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Within a year from the date of production, they will retain their optimal flavor

This review, published in the American Journal of Preventive Medicine in 2014, looked at 76 of the best available studies on e-cigarettes: "Due to many methodological problems, severe conflicts of interest, the relatively few and often small studies, the inconsistencies and contradictions in results, and the lack of long-term follow-up no firm conclusions can be drawn on the safety of [e-cigarettes]." The researchers also found that in 26 of the studies reviewed, the authors had declared a conflict of interest

Some people may combine the patch with other forms of nicotine replacement to help taper off cigarettes safely