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The study used a single high dose and did not evaluate symptoms, disease outcomes or long-term use

Nature 433:7377 Brer A, Deitmer JW, Brer S (2004) Astroglial glutamine transport by system N is upregulated by glutamate

J Biol Chem (1991) 266:783441

For example, T cell activation induces the expression of ASCT2 (encoded by Slc1a5 ), which mediates glutamine uptake and further leads to the activation of mTORC1 [211]