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Nonadherence rates are notably high for oral antipsychotics,Reference Garcia, Martinez-Cengotitabengoa and Lopez-Zurbano 11 with reported rates of partial or complete lack of adherence to antipsychotic medications as high as 25% within the first 1014 days after hospital discharge.Reference Velligan, Lam and Ereshefsky 12 Indeed, it is often the patients who fail to adhere to oral antipsychotic medication who are candidates for LAI treatment.Reference Kane 13 Obviously, these individuals may continue to struggle with adherence to even a short, 21-day oral aripiprazole supplementation regimen after their first AL injection

Among these, mesenchymal stem cells (MSCs) have become the most promising therapeutic tools due to their self-renewal, multilineage differentiation potential, low immunogenicity, and immunomodulatory properties (Ogaili et al., 2025)

Side effects are rare but may include mild redness or swelling at the injection site

updated November 2024