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Furthermore, a significant number of patients exhibit intolerance to angiotensinconverting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs)

459 Conversely, ELK3 reduces triple-negative breast cancer sensitivity to cisplatin by inhibiting fission and ROS generation, 460 and DNA damage agents enhance TCA cycle metabolic adaptability through OPA1-mediated mitochondrial fusion

Hexokinase Is an innate immune receptor for the detection of bacterial peptidoglycan

Proinflammatory effects of free heme have been shown to induce up-regulation of adherence molecules in other organs including the gut, liver, and pancreas (Wijayanti et al., 2004)