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Through establishing an interleukin (IL)-1-stimulated chondrocytes, it was found that L-theanine could inhibit the nuclear factor kappa B (NF-B) pathway, thereby reducing the expression of proinflammatory factors, including cyclooxygenase-2 (COX-2), prostaglandin E2, inducible nitric oxide synthase, as well as NO, and protect the degradation of extracellular matrix ( In summary, the anti-inflammatory activity of L-theanine can be associated with inhibiting the expression of inflammatory factors and inflammation-related signaling pathways

Platelet GPIb is a mediator and potential interventional target for NASH and subsequent liver cancer

10.2147/DDDT.S464100 [DOI] [PMC free article] [PubMed] [Google Scholar] Ramesh P., Jagadeesan R., Sekaran S., Dhanasekaran A., Vimalraj S