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[87] found that ox-LDL stimulated in ECs NLRP3 inflammasome activation, increased IL-1 and IL-18 maturation and secretion, increased intracellular ROS and increased lactate dehydrogenase (LDH) release in ECs

for 12 days) increased chemosensitivity of paclitaxel in Ehrlich ascites carcinoma model, where it promoted expression of tumor suppressor genes (p21, Brca1 and Hic1), induction of apoptosis-related markers (cleaved caspase-3,7 and 12 and PARP), modulation of p53 and JAK-STAT signaling and reduction of phosphorylated p65 and Akt [116]

Figure 4 DMB Promotes the Recovery of KCl-, Ach-, BaCl 2 -, or HA-Induced Intestine Smooth Muscle Contraction To further determined the spasmolytic activity of DMB, spasmogens, such as KCl, ACh, BaCl 2 , or HA, induced intestinal smooth muscle contraction models were used

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