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Articles of experimental studies, clinical observational studies, meta-analyses, and high-quality narrative or systematic reviews were first selected

This strengthens the role of lithium in maintaining synaptic function by GSK-3 and IMPA-dependent mechanisms (see Figure 1B)

As MASLD and hypertension are common co-morbidities, a study regarding differences in GSTM1 and GSTO1 protein expression in normotensive and hypertensive rats was performed which showed significant GSTO1 downregulation and no change in GSTM1 levels in hypertensive rats (Svoboda and Kawaja 2012)