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278 These pathways lead to granzyme release, ROS production, 279 and the activation of transcription factors, including STAT3, 280 NF-B, activator protein 1 (AP-1), 281 and cAMP-responsive element-binding protein (CREB), 277 which further contributes to the expression of pro-inflammatory cytokines, co-stimulatory molecules, and complement components

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Description IGF-1 LR3 Peptide IGF-1 LR3 Peptide (Long Arg3 Insulin-Like Growth Factor-1) 1mg (Lyophilized Peptide) For Research Use Only IGF-1 LR3 is a synthetic analog of human Insulin-Like Growth Factor-1 (IGF-1), modified to extend its half-life in vitro through substitution of arginine at position 3 and removal of the first three amino acids of the native IGF-1 sequence