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Before we go and find out what the big deal with Matrixyl 3000 is, let's just focus on Palmitoyl Tripeptide-1 itself for a bit

Available reports are listed in the COA Library

Compared with unipolar depression, bipolar depressed subjects had significantly decreased connectivity between pgACC and amygdala and dorsomedial thalamus (150) Moreover, a separate group of investigators reported a more intense activation of ventral striatal, thalamic, hippocampal, amygdala, caudate nucleus/putamen, vmPFC, ventrolateral PFC, and ACC in bipolar depressed individuals compared with MDD and a healthy control group, especially in response to mildly and intensely fearful and sad, and mildly happy expressions (104)

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