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Toxicol In Vitro 1(68):104958 Lee JH, Choi SH, Baek MW, Kim MH, Kim HJ, Kim SH, Oh SJ, Park HJ, Kim WJ, Jung JY (2013) CoCl 2 induces apoptosis through the mitochondria-and death receptor-mediated pathway in the mouse embryonic stem cells

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Peptides that specifically bind tumor endothelial cells have also been used to target either therapeutic antibodies or chemokines to the tumor microenvironment to improve efficacy and decrease toxicity [325, 326]