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SAM acts as a key methyl donor for most methylation modifications, including the methylation of DNA, RNA, lipids and histones, and also participates in polyamine biosynthesis, which has a function in multiple cellular processes including regulation of chromatin structure, transcription and translation, DNA stabilization, cell growth and proliferation [50]

Wang M, Jiang S, Zhou L, Yu F, Ding H, Li P, Zhou M, Wang K

the structure is similar to cysteine, only the sulfur atom is replaced by selenium.In 1978, Forstrom and Tappel identified the active center of glutathione peroxidase as Selenium Cysteine(Sec), which is the 21st amino acid known to be involved in the biosynthesis of proteins

Structural brain imaging studies in alcoholics have shown defects in the brain regions involved in memory, cognition and emotional processing