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33 The importance of biocompatible macrocyclisation strategies The innovation of solid-phase peptide synthesis (SPPS) by Merrifield in the 1960s radically revolutionised the chemical synthesis of peptides via a facile, efficient and automated platform, enabling large scale production of bioactive peptides

The peptide research and studies overview contextualizes how preclinical evidence fits into the broader landscape of peptide development

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This combination of hydrophobic and hydrophilic characteristics allows for effective interaction with lipid membranes and more compounds to be entrapped in the skin