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As the binding activity of FH-Fc constructs to their FH-binding partners from pathogens is one of the determining factors for their efficacy, our findings raise the possibility that S2635 and S2782 differ in their capability to bind to different spirochete FH-binding protein variants

In addition to identifying novel targets for therapeutic interventions, exposure models provide a comprehensive assessment of the pharmacological efficacy of both existing and emerging medicines for COPD

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Biosens Bioelectron 2011, 29 (1):132-139