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Bottom row: NMR solution structure of the nucleocapsid protein from human immunodeficiency virus type 1 group M subtype B (isolate MN) (PDB ID: 1AAF) (Summers et al., 1992), NMR structure of Megabalanus rosa Cement Protein 20 (PDB ID: 6LEK) (Mohanram et al., 2019), NMR structure of the major house dust mite allergen Der p 2 (PDB ID: 1A9V) (Mueller et al., 1998), and X-ray crystal structure of E

It is known that by 1 week of cuprizone administration, microglia are activated in the corpus callosum 23 , with astrocytes showing morphological changes as early as 1 week and increasing in density by 3 weeks 24