interaction of chloroacetamide electrophiles with cellular glutathion

interaction of chloroacetamide electrophiles with cellular glutathion Covalent inhibitors bacterial peptidoglycan biosynthesis enzyme MurA warhead Expanding the Chemistry of Dihaloacetamides

Name: interaction of chloroacetamide electrophiles with cellular glutathion Covalent inhibitors bacterial peptidoglycan biosynthesis enzyme MurA warhead Expanding the Chemistry of Dihaloacetamides
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SKU: 82786359087
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Expanding the Chemistry of Dihaloacetamides as Tunable Electrophiles for Reversible Covalent Targeting of Cysteines Journal of Medicinal Chemistry Targeting a Therapy Resistant Cancer Cell State Using Masked Electrophiles as GPX4 Inhibitors bioRxiv Delineating cysteine reactive compound modulation of cellular proteostasis processes Nature Chemical Biology Glutathione Dynamics in Subcellular Compartments and Implications for Drug Development PMC

SKU: 82786359087 · From www.marsberger-treibhaus.de

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It is not approved for human medical use

PMID: 11124012

While these drugs can temporarily alleviate or stabilize symptoms, they are unable to stop the long-term progression of the disease and are associated with various side effects