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These results collectively demonstrated that DHA-N@M exhibited both high FPF and optimal MMAD, ensuring efficient deep lung delivery while minimizing oropharyngeal deposition, thereby confirming its suitability as an excellent pulmonary delivery carrier

When conjugated folates adhere to an FR on a cell surface, Figure 1 shows how the FR present on the surface of the cell after binding to the conjugate aids in the release of an initial quantity of the therapeutic load into the cytoplasm which is referred to as the final stage in the receptor-mediated absorption of folate drug ligand-conjugates

Dai X, Bu X, Gao Y, Guo J, Hu J, Jiang C, et al

The SGLT2 inhibitor empagliflozin attenuates atherosclerosis progression by inducing autophagy