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7 4) Example translational/clinical investigation Ipamorelin has also been investigated clinically as a ghrelinreceptor agonist in a phase 2 randomized proofofconcept study for postoperative ileus , where it was reported as well tolerated but did not significantly improve the primary efficacy endpoint versus placebo (as reported)

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Grimberg A, DiVall SA, Polychronakos C, Allen DB, Cohen LE, Quintos JB, Rossi WC, Roth CL, Murad MH