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This low energy gain can sometimes be improved by proton-substrate symport, i.e., lactic acid excretion, generating a proton gradient: since this system is electrogenic it can increase the energy yield of LAB

Growth hormone secretagogues (GHS) such as Ipamorelin and MK-677 act on ghrelin receptors (GHS-R1a) to stimulate GH release through a parallel pathway