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Most notably, domperidonea dopamine receptor antagonist that does not typically cross an intact BBBwas found to exert central behavioral effects in lesioned animals, indicating a functional breach of the barrier (Carvey et al

539 Low dose of erythropoietin can selectively induce erythrocytosis, accompanied by significant ferroptosis and lipid peroxidation, which further aggravate atherosclerosis

R., Rubin, R

Taken together, although growing evidence suggests ceramide can induce insulin resistance, further studies are needed to elucidate the molecular mechanism whereby ceramides impair insulin signaling or glucose transport translocation